Butabarbital decreases effects of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Coadministration of CYP3A4 inducers may well decrease sufentanil degrees and efficacy, maybe precipitating withdrawal syndrome in people which have made physical dependence to sufentanil. Discontinuation of concomitantly used CYP3A4 inducers... https://carolynm876ygn5.webdesign96.com/profile