An extensive literature evaluate of studies among 1995 and 2018 was executed using the electronic databases PubMed and EBSCO Host. Queries have been done applying the following terms: whole knee arthroplasty (TKA); cyclooxygenase-2 inhibitors; bracing; physical therapy; weight-loss; knee; treatment; therapeutics; OA; intra-articular injection; hyaluronic acid; corticosteroid; and alte... https://www.theorthopaedicandpainpractice.com/non-surgical-treatments-for-knee-joint-pain/