The recognized impression of those PTMs on ATXN2’s purpose and SCA2 pathogenesis remains limited. In other polyQ illnesses, many scientific studies advised that proteolytic cleavage of polyQ proteins could Perform a vital purpose in pathogenesis [36, 45]. Aligned with this strategy, the presence of an enriched 42 kDa fragment within the https://stattic11098.bluxeblog.com/60390080/about-recombinant-gst